Vitamins, minerals and amino acids form the brick-and-mortar foundation of a healthy body. The 2020 Dietary Guidelines for Americans reported that the foods and beverages people consume have a profound impact on their health, and many Americans fall short in obtaining sufficient quantities of these important nutrients. The scientific connection between food and health has been documented for decades, with substantial evidence showing that healthy dietary patterns can help people achieve and maintain good health. Supplementation with vitamins, minerals and amino acids can play a valuable role in helping to fill nutritional gaps.^‡