Every day, we are exposed to chemicals, contaminants, pesticides and hormones in our environment, medications, water, food supply, and more. The body’s natural detoxification process involves a highly complex interplay among the kidneys, lungs, skin, lymph systems, and, most importantly, the liver. The liver functions in two phases to transform toxins so they can be eliminated from the body. Each phase relies on specific nutrients for optimal performance, with phase one setting the stage for how well the liver performs during phase two. The two phases depend on different nutrients and must be in balance with one another to function optimally. Supplementation with targeted nutrients may be an effective approach for supporting optimal liver function and overall health.